Clinical Trials

Clinical Trials for Brain Tumor Patients

It is important to know about clinical trial options but it can be confusing and overwhelming to understand what clinical trial may be best for you or your loved one. This section is provided to provide some answers to questions about research studies and how they are conducted, as well as links to sites that list current recruiting trials for which you or your loved one may be eligible.

Clinical trials are studies designed to test up-and-coming treatments. There are many motivating factors for participating in a clinical trial, for example, some wish to try a new and promising treatment method; others desire to contribute to the development of future treatment, or to help find a cure. Every clinical trial has specific criteria a patient must meet in order to participate. Some trials can be joined before your first surgery, others during radiation, others at the point of recurrence. Most brain tumor clinical trials are conducted after standard of care treatments have been implemented.

Clinical Trial Phases

    Phase I: Determine maximum tolerated dose (how much, how safe, how often?) 
    Phase II: Evaluate effectiveness (is this treatment helpful?) 
    Phase III: Compares a new treatment to the standard treatment to determine which is more effective. (Is the new treatment better?)

Clinical Trials Currently Recruiting at Orlando Health UF Health Cancer Center

Learn more about our Active Clinical Trials.

Accessing Clinical Trial Information

The following resources offer clinical trial databases to search for trials. Follow the directions below to find a clinical trial.

National Brain Tumor Society Clinical Trial Matching Service

Click here to visit the National Brain Tumor Society Clinical Trial Matching Service website. Or alternatively you can call 877.769.4812 to speak with a clinical trial navigator specially trained to help you find clinical trials that match your tumor type. This service is available business hours Monday through Friday from 8:30am to 6:30pm ET.

  • Click here to visit
  • Click on the “Find a Clinical Trial” link.
  • Under “Type of Cancer” find your tumor type and specify if you are looking for adult or pediatric brain tumor clinical trials.
  • Enter your zip code and click on the “Search” button.

A list of clinical trials will appear if your search criteria has found a match and you should be able to click on the trials listed. Each trial will have a name, current phase (i.e., I, II, III), trial summary, eligibility information, contact information, and locations.

  • Click here to visit
  • Click on “Find a Clinical Trial” from the list of links on the home page.
  • Enter your search criteria, such as tumor type, treatment type, trial phase, age group, country, etc. Once you have entered this information click on the “Find Matching Clinical Trials” button.
  • A list of clinical trials will appear with the treatment or trial name, location, and the date it was last updated on the website.
  • To find out more about a particular clinical trial, click on the “Details” link on the left hand side of the listing. The treatment name, phase, age group, tumor type, trial information, contact information, and locations will appear.